DNA computing is a form of computing which uses DNA, biochemistry and molecular
biology, instead of the traditional silicon-based computer technologies.
DNA computing, or, more generally, biomolecular computing, is a fast-developing interdisciplinary area. Research and
development in this area concerns theory, experiments, and applications of
DNA computing. The term "molectronics" has sometimes been used, but this term had already been used for an earlier technology, a then-unsuccessful rival of the first integrated circuits; this term has also been used more generally, for molecular-scale technology.
Contents
1 History
2 Capabilities
3 Methods
3.1 DNAzymes
3.2 Enzymes
3.3 Toehold exchange
3.4 Algorithmic self-assembly
4 See also
5 References
6 Further reading
7 External links
In consanguineous families, as a result of inheriting the same genomic segments through both parents, the individuals have stretches of their genomes that are homozygous. This situation leads to the prevalence of recessive diseases among the members of these families. Homozygosity mapping is based on this observation and several recessive disease genes have been discovered with the help of this technique in consanguineous families. The researchers typically use SNP arrays to determine the homozygous regions and then search for the disease gene by sequencing the genes within this candidate disease loci.
